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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HIST1H1E All Species: 36.97
Human Site: S78 Identified Species: 81.33
UniProt: P10412 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P10412 NP_005312.1 219 21865 S78 Y D V E K N N S R I K L G L K
Chimpanzee Pan troglodytes XP_001172808 221 22291 S79 Y D V E K N N S R I K L G L K
Rhesus Macaque Macaca mulatta P40286 208 22075 S82 Y D V E K N N S R I K L S L K
Dog Lupus familis XP_853847 290 29282 S133 Y D V E K N N S R I K L G L K
Cat Felis silvestris
Mouse Mus musculus P43274 219 21959 S78 Y D V E K N N S R I K L G L K
Rat Rattus norvegicus P15865 219 21969 S78 Y D V E K N N S R I K L G L K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515094 223 22581 S78 Y D V E K N N S R I K L G L K
Chicken Gallus gallus P08284 219 22026 S79 Y D V E K N N S R I K L G L K
Frog Xenopus laevis P06893 220 22422 S82 Y D V D K N N S R L K L A L K
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P02255 256 26341 P88 C D A Q K L A P F I K K Y L K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P19375 205 22145 T78 E K G K L V Q T K G K G A S G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.5 55.7 57.2 N.A. 94 95.4 N.A. 79.8 73.9 58.6 N.A. N.A. 43.3 N.A. N.A. 41.1
Protein Similarity: 100 87.3 68 62 N.A. 95.4 97.2 N.A. 87 79.4 66.3 N.A. N.A. 52.3 N.A. N.A. 50.6
P-Site Identity: 100 100 93.3 100 N.A. 100 100 N.A. 100 100 80 N.A. N.A. 40 N.A. N.A. 6.6
P-Site Similarity: 100 100 93.3 100 N.A. 100 100 N.A. 100 100 93.3 N.A. N.A. 46.6 N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 0 10 0 0 0 0 0 19 0 0 % A
% Cys: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 91 0 10 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 10 0 0 73 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % F
% Gly: 0 0 10 0 0 0 0 0 0 10 0 10 64 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 82 0 0 0 0 0 % I
% Lys: 0 10 0 10 91 0 0 0 10 0 100 10 0 0 91 % K
% Leu: 0 0 0 0 10 10 0 0 0 10 0 82 0 91 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 82 82 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 10 0 0 10 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 82 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 82 0 0 0 0 10 10 0 % S
% Thr: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % T
% Val: 0 0 82 0 0 10 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 82 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _